Immunological Sciences

Adipsin Rabbit Polyclonal Antibody

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Catalog Number:AB-3606
Conjugate:Unconjated
Size:100 ug
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:POLY
Immunogen:Synthesized peptide derived from human Adipsin AA range: 101-150
Reactivity:Human, Mouse, Rat
Applications:Western Blot:   1:1000-2000
Molecular Weight:28kDa
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form:Liquid
Synonyms:Complement factor D (EC 3.4.21.46;Adipsin;C3 convertase activator;Properdin factor D)

Applications

Western Blot:   1:1000-2000

Immunogen

Synthesized peptide derived from human Adipsin AA range: 101-150

Target Background

catalytic activity:Selective cleavage of Arg-|-Lys bondin complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.,disease:Defects in CFD are the causeof complement factor D deficiency . This deficiency predisposes to invasive meningococcal disease.,function:Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.,online information:CFD mutation db,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.

Synonyms:Complement factor D (EC 3.4.21.46;Adipsin;C3 convertase activator;Properdin factor D)

Storage

Store at -20℃. Avoid repeated freeze-thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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