Immunological Sciences

ADRB2 Mouse Monoclonal Antibody

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Catalog Number:MABN81790
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human ADRB2 (AA: 302-413) expressed in E. Coli.
Reactivity:Human,Rat
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:46.5kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:BAR; B2AR; ADRBR; ADRB2R; BETA2AR

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human ADRB2 (AA: 302-413) expressed in E. Coli.

Target Background

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

Synonyms:BAR; B2AR; ADRBR; ADRB2R; BETA2AR

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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