Immunological Sciences

AKAP 2 Rabbit Polyclonal Antibody

No images available

Catalog Number:ABN06722
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human AKAP2. AA range:71-120
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,ELISA 1:10000-1:20000
Molecular Weight:96kDa
Purification:Affinity purification
Form:Liquid
Synonyms:AKAP2; KIAA0920; PRKA2; A-kinase anchor protein 2; AKAP-2; AKAP-KL; Protein kinase A-anchoring protein 2; PRKA2

Applications

WB 1:500-1:2000,ELISA 1:10000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human AKAP2. AA range:71-120

Target Background

The protein encoded by this gene binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. The encoded protein mediates signals carried by cAMP and may be involved in creating polarity in certain signaling processes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],caution:It is uncertain whether Met-1 or Met-3 is the initiator.,function:Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP.,miscellaneous:Can be differentially expressed as a natural AKAP2-PALM2 chimeric protein.,similarity:Belongs to the paralemmin family.,tissue specificity:Expressed in infantile heart and muscle, and fibroblasts.,

Synonyms:AKAP2; KIAA0920; PRKA2; A-kinase anchor protein 2; AKAP-2; AKAP-KL; Protein kinase A-anchoring protein 2; PRKA2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

No documents available.