AKR1C1 Mouse Monoclonal Antibody

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Catalog Number:MABN82996
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:A synthetic peptide of human AKR1C1/AKR1C2
Reactivity:Human,Rabbit
Applications:WB 1:500-1:1000,IHC 1:200-1:400,FC 1:200-1:400
Molecular Weight:36.8kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:C9;DD1;DDH;DDH1;H-37;HBAB;MBAB;HAKRC;DD1/DD2;2-ALPHA-HSD;20-ALPHA-HSD

Applications

WB 1:500-1:1000,IHC 1:200-1:400,FC 1:200-1:400

Immunogen

A synthetic peptide of human AKR1C1/AKR1C2

Target Background

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

Synonyms:C9;DD1;DDH;DDH1;H-37;HBAB;MBAB;HAKRC;DD1/DD2;2-ALPHA-HSD;20-ALPHA-HSD

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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