ALIX Rabbit Monoclonal Antibody

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Catalog Number:MABN84023
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human PDCD6IP
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,FC 1:20-1:100
Molecular Weight:Calculated MW: 96 kDa ; Observed MW: 97 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:AIP1; Alix; DRIP4; Hp95; PDCD6IP;;PDCD6IP

Applications

WB 1:1000-1:2000,FC 1:20-1:100

Immunogen

A synthesized peptide derived from human PDCD6IP

Target Background

Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction integrity. Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes.

Synonyms:AIP1; Alix; DRIP4; Hp95; PDCD6IP;;PDCD6IP

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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