Immunological Sciences

alpha 1 Fetoprotein Rabbit Monoclonal Antibody

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Catalog Number:MABN87175
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human alpha 1 Fetoprotein
Reactivity:Human
Applications:WB 1:2000-1:20000,IHC 1:100-1:200,ICC/IF 1:100-1:200,FC 1:10-1:100,IP 1:10-1:100
Molecular Weight:Calculated MW:69 kDa; Observed MW:70 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:AFPD; FETA; HPAFP

Applications

WB 1:2000-1:20000,IHC 1:100-1:200,ICC/IF 1:100-1:200,FC 1:10-1:100,IP 1:10-1:100

Immunogen

Recombinant protein of human alpha 1 Fetoprotein

Target Background

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]

Synonyms:AFPD; FETA; HPAFP

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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