alpha/beta Synuclein Rabbit Monoclonal Antibody
Western blot analysis of extracts from Mouse brain tissue using alpha/beta Synuclein Rabbit Monoclonal Antibody at 1:1000.
| Catalog Number: | MABN86637 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | Monoclonal |
| Immunogen: | A synthetic peptide of human alpha Synuclein |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:5000,ICC/IF 1:50-1:100,FC 1:20-1:50 |
| Molecular Weight: | 18 kDa |
| Purification: | Affinity purification |
| Form: | Liquid |
| Synonyms: | PD1; NACP; PARK1; PARK4 |
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Applications
WB 1:1000-1:5000,ICC/IF 1:50-1:100,FC 1:20-1:50
Immunogen
A synthetic peptide of human alpha Synuclein