Immunological Sciences

Alpha Fodrin (15V11) Rabbit Monoclonal Antibody

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Catalog Number:MABN06793
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Alpha Fodrin
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000
Molecular Weight:285kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Alpha II Spectrin; EIEE5; Fodrin alpha chain; NEAS; SPECA; Spectrin; Spna2; SPTAN1;

Applications

WB 1:500-1:2000

Immunogen

A synthetic peptide of human Alpha Fodrin

Target Background

Fodrin (also named nonerythroid spectrin) is a universally expressed membrane-associated cytoskeletal protein consisting of alpha- and beta-subunits (1). This protein is important for maintaining normal membrane structure and supporting cell surface protein function (1). Alpha-fodrin is one of the primary targets cleaved by caspases during apoptosis. Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.

Synonyms:Alpha II Spectrin; EIEE5; Fodrin alpha chain; NEAS; SPECA; Spectrin; Spna2; SPTAN1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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