alpha Synuclein Rabbit Monoclonal Antibody
Western blot analysis of Alphasynuclein in rat Brain lysates using alpha Synuclein antibody.
| Catalog Number: | MABN01639 |
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | Monoclonal |
| Immunogen: | A synthetic peptide corresponding to target protein |
| Reactivity: | Human,Rat |
| Applications: | WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50 |
| Molecular Weight: | Calculated MW: 14 kDa; Observed MW: 18 kDa |
| Purification: | Affinity Purification |
| Form: | Liquid |
| Synonyms: | SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP |
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).
Applications
WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50
Immunogen
A synthetic peptide corresponding to target protein
