Immunological Sciences

AMPK gamma 1 Rabbit Monoclonal Antibody

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Catalog Number:MABN86981
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human AMPK gamma 1
Reactivity:Human, Mouse, Rat
Applications:WB 1:500-1:2000,FC 1:20-1:50,IP 1:20-1:50
Molecular Weight:Calculated MW:38 kDa; Observed MW:38 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:AMPKG

Applications

WB 1:500-1:2000,FC 1:20-1:50,IP 1:20-1:50

Immunogen

A synthetic peptide of human AMPK gamma 1

Target Background

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Synonyms:AMPKG

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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