Angiopoietin 1 Rabbit Polyclonal Antibody

No images available

Catalog Number:ABN00085
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic peptide of human Angiopoietin 1
Reactivity:Human,Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 58 kDa; Observed MW: 58 kDa
Purification:Affinity Chromatography
Form:Liquid
Synonyms:ANGPT1; KIAA0003; Angiopoietin-1; ANG-1

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human Angiopoietin 1

Target Background

Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.

Synonyms:ANGPT1; KIAA0003; Angiopoietin-1; ANG-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

No documents available.