Angiopoietin 1 Rabbit Polyclonal Antibody

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Catalog Number:ABN03349
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic peptide of human Angiopoietin 1
Reactivity:Human,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ELISA 1:5000-1:20000
Molecular Weight:Calculated MW: 58 kDa; Observed MW: 58 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ANGPT1; KIAA0003; Angiopoietin-1; ANG-1

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ELISA 1:5000-1:20000

Immunogen

A synthetic peptide of human Angiopoietin 1

Target Background

Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.

Synonyms:ANGPT1; KIAA0003; Angiopoietin-1; ANG-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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