Immunological Sciences

Angiopoietin 2 Rabbit Monoclonal Antibody

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Catalog Number:MABN83990
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human Angiopoietin 2
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,IHC 1:100-1:200
Molecular Weight:Calculated MW: 57 kDa ; Observed MW: 50 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:AGPT 2; Agpt2; ANG2; Angiopoietin 2a; Angiopoietin 2B; Angiopoietin2; ANGPT 2; Angpt2; Tie2 ligand;;Angiopoietin 2

Applications

WB 1:1000-1:2000,IHC 1:100-1:200

Immunogen

A synthesized peptide derived from human Angiopoietin 2

Target Background

Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Synonyms:AGPT 2; Agpt2; ANG2; Angiopoietin 2a; Angiopoietin 2B; Angiopoietin2; ANGPT 2; Angpt2; Tie2 ligand;;Angiopoietin 2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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