Angiotensin Converting Enzyme 1 Rabbit Monoclonal Antibody

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Catalog Number:MABN85285
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse Angiotensin Converting Enzyme 1
Reactivity:Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight:Calculated MW: 151 kDa; Observed MW: 180 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ACE; Dipeptidyl carboxypeptidase I; Kininase II

Applications

WB 1:500-1:1000,IHC 1:50-1:100

Immunogen

Recombinant protein of mouse Angiotensin Converting Enzyme 1

Target Background

Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm.

Synonyms:ACE; Dipeptidyl carboxypeptidase I; Kininase II

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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