Anti-beta Amyloid 1-40 Rabbit pAb
IHC analysis of Aβ40 . Sample: Mouse Alzheimer's brain , 4% PFA 12-24h. Antigen retrieval: Citrate buffer ,98℃,20 min. Blocking buffer: 3% BSA in PBS , RT, 30min. Primary antibody: 1: 400, 4℃ overnight. Secondary antibody: HRP Goat Anti-Rabbit lgG , 1: 200 RT 1h.
| Catalog Number: | ABS111197 |
| Conjugate: | unconjugated |
| Size: | 100 μL |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Aβ40 |
| Reactivity: | Mouse, Rat |
| Applications: | IHC/IF<br/>1: 400-1: 1000 |
| Purification: | Affinity purification |
| Form: | Liquid |
Most of autosomal dominant familial AD can be attributed to mutations in one of three genes: those encoding amyloid precursor protein (APP) and presenilins 1 and 2 Most mutations in the APP and presenilin genes increase the production of a small protein called Aβ42, which is the main component of senile plaques. Some of the mutations merely alter the ratio between Aβ42 and the other major forms—particularly Aβ40—without increasing Aβ42 levels
Applications
IHC/IF<br/>1: 400-1: 1000
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Aβ40
