Anti-ICAM1 Rabbit pAb
WB analysis of ICAM1 . Sample: Protein treated by RIPA Lysis Buffer . Blocking buffer: 3% Nonfat dry milk in TBST, RT, 1h. Primary antibody: 1: 1000, 4℃ overnight. Secondary antibody: HRP Goat Anti-Rabbit lgG , 1: 3000, RT, 1h.
| Catalog Number: | ABS11106 |
| Conjugate: | unconjugated |
| Size: | 100 μL |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1 |
| Reactivity: | Mouse, Rat |
| Applications: | IHC/IF<br/>1: 500-1: 5000 |
| Molecular Weight: | 89/100 kDa |
| Purification: | Affinity purification |
| Form: | Liquid |
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.(Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins . Acts as a receptor for Coxsackievirus A21 capsid proteins . Upon Kaposis sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell . Images
Applications
IHC/IF<br/>1: 500-1: 5000
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1
