Anti-Kininogen 1 Rabbit Monoclonal Antibody

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Catalog Number:MABN86582
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Kininogen 1
Reactivity:Human
Applications:WB 1:2000-1:20000,IHC 1:100-1:200,IP 1:10-1:100
Molecular Weight:Calculated MW:72 kDa; Observed MW:
Purification:Affinity Purification
Form:Liquid
Synonyms:BK; BDK; KNG

Applications

WB 1:2000-1:20000,IHC 1:100-1:200,IP 1:10-1:100

Immunogen

A synthetic peptide of human Kininogen 1

Target Background

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014]

Synonyms:BK; BDK; KNG

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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