Anti-Phospho-TAU (S202/T205) Rabbit pAb
WB analysis of P-TAU . Sample: Protein treated by RIPA Lysis Buffer . Blocking buffer: 3% Nonfat dry milk in TBST, RT, 1h. Primary antibody: 1: 1000, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG , 1: 3000, RT, 1h.
| Catalog Number: | ABS113883 |
| Conjugate: | unconjugated |
| Size: | 100 μL |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human TAU (S202/T205) |
| Reactivity: | Human, Mouse, Rat |
| Applications: | WB 1: 500-1: 1000<br/>IHC/IF 1: 600-1: 1200 |
| Molecular Weight: | 79 kDa / 50-80 kDa |
| Purification: | Affinity purification |
| Form: | Liquid |
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity .The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both .Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Applications
WB 1: 500-1: 1000<br/>IHC/IF 1: 600-1: 1200
Immunogen
KLH conjugated Synthetic phosphopeptide corresponding to Human TAU (S202/T205)
