Anti-SQSTM1/p62 Rabbit pAb

Western blot analysis of SQSTM1 p62 at dilution of 1: 500

Western blot analysis of SQSTM1 p62 at dilution of 1: 500

Catalog Number:ABS11239
Conjugate:unconjugated
Size:100 μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Immunogen:Recombinant protein corresponding to Mouse SQSTM1
Reactivity:Human, Mouse, Rat
Applications:Western Blot:1:500-1:1000 Immunocytochemistry- Immunofluorescence : 1:600
Molecular Weight:60kDa
Purification:Affinity purification
Form:Liquid
Synonyms:None

The product of SQSTM1 gene, Sequestosome-1, also kown as ubiquitin-binding protein p62, is an autophagosome cargo protein that targets other proteins that bind to it for selective autophagy. By interacting with GATA4 and targeting it for degradation, it can inhibit GATA-4 associated senescence and senescence-associated secretory phenotype.

Applications

Western Blot:1:500-1:1000 Immunocytochemistry- Immunofluorescence : 1:600

Immunogen

Recombinant protein corresponding to Mouse SQSTM1

Target Background

The product of SQSTM1 gene, Sequestosome-1, also kown as ubiquitin-binding protein p62, is an autophagosome cargo protein that targets other proteins that bind to it for selective autophagy. By interacting with GATA4 and targeting it for degradation, it can inhibit GATA-4 associated senescence and senescence-associated secretory phenotype.

Synonyms:None

Storage

Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Western blot analysis of SQSTM1 p62 at dilution of 1: 500

Immunocytochemistry analysis of 4% paraformaldehyde-fixed Hela cell untreatd using p62 at dilution of 1: 1000

Immunocytochemistry analysis of 4% paraformaldehyde-fixed Hela cell with chloroquine treated using p62 at dilution of 1: 1000

Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH/3T3 cell with chloroquine treated and untreatd using P62 at dilution of 1: 2000

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