Anti-SQSTM1/p62 Rabbit pAb
Western blot analysis of P62 at dilution of 1: 500 Lane 1: HeLa cell lysate Lane 2: HeLa cell lysate Lane 3: NIH3T3 cell lysate Lane 4: NIH3T3 cell lysate Lane 5: HepG2 cell lysate Lane 6: MCF7 cell lysate Lane 7: A549 cell lysate Lane 8: L929 cell lysate Lane 9: PC-12 cell lysate
| Catalog Number: | ABS11531 |
| Conjugate: | unconjugated |
| Size: | 100 μL |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Human SQSTM1 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | WB:1: 500-1: 1000 Immunohistochemistry: 1:500 -1:1000 Immunocitochemistry-immunofluorescence: 1:500-1:1000 |
| Molecular Weight: | 62 kDa |
| Purification: | Affinity purification |
| Form: | Liquid |
The product of SQSTM1 gene, Sequestosome-1, also kown as ubiquitin-binding protein p62, is an autophagosome cargo protein that targets other proteins that bind to it for selective autophagy. By interacting with GATA4 and targeting it for degradation, it can inhibit GATA-4 associated senescence and senescence-associated secretory phenotype.
Applications
WB:1: 500-1: 1000 Immunohistochemistry: 1:500 -1:1000 Immunocitochemistry-immunofluorescence: 1:500-1:1000
Immunogen
KLH conjugated Synthetic peptide corresponding to Human SQSTM1
