APBA2 Mouse Monoclonal Antibody

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Catalog Number:MABN81811
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human APBA2 (AA: 15-158) expressed in E. Coli.
Reactivity:Human
Applications:ICC 1:50-1:200,ELISA 1:5000-1:20000
Molecular Weight:82.5kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091

Applications

ICC 1:50-1:200,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human APBA2 (AA: 15-158) expressed in E. Coli.

Target Background

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms:X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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