APG5L/ATG5 Rabbit Monoclonal Antibody

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Catalog Number:MABN86454
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human APG5L/ATG5
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,FC 1:100-1:200
Molecular Weight:Calculated MW:33 kDa; Observed MW:55 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,FC 1:100-1:200

Immunogen

A synthetic peptide of human APG5L/ATG5

Target Background

The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Synonyms:ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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