APLP-1 rabbit Polyclonal Antibody
Western Blot analysis of extracts from K562 cells, using APLP-1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000
| Catalog Number: | ABE3788 |
| Conjugate: | unconjugated |
| Size: | 100 ug |
| Concentration: | 1 mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | Polyclonal |
| Immunogen: | Synthesized peptide derived from APLP-1 . at AA range: 360-440 |
| Reactivity: | Human;Mouse |
| Applications: | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications. |
| Molecular Weight: | 72kD |
| Purification: | The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Form: | liquid |
| Synonyms: | APLP1; Amyloid-like protein 1; APLP; APLP-1 |
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
Applications
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from APLP-1 . at AA range: 360-440
