Immunological Sciences

Apolipoprotein CI (10F18) Rabbit Monoclonal Antibody

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Catalog Number:MABN07052
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Apolipoprotein CI
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,IP 1:20-1:50
Molecular Weight:9kDa
Purification:Affinity purification
Form:Liquid
Synonyms:APO C1; Apo CI; APOC 1; ApoC I; APOC1; APOC1B; ApolipoproteinCI;

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,IP 1:20-1:50

Immunogen

Recombinant protein of human Apolipoprotein CI

Target Background

Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification. Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.

Synonyms:APO C1; Apo CI; APOC 1; ApoC I; APOC1; APOC1B; ApolipoproteinCI;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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