Immunological Sciences

Apolipoprotein E Rabbit Monoclonal Antibody

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Catalog Number:MABN86823
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of mouse Apolipoprotein E
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:500-1:5000,ICC/IF 1:200-1:500,FC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW:36 kDa; Observed MW:36 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:AD2; LPG; APO-E; ApoE4; LDLCQ5

Applications

WB 1:500-1:2000,IHC 1:500-1:5000,ICC/IF 1:200-1:500,FC 1:50-1:100,IP 1:20-1:50

Immunogen

A synthetic peptide of mouse Apolipoprotein E

Target Background

The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]

Synonyms:AD2; LPG; APO-E; ApoE4; LDLCQ5

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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