APPL Rabbit Monoclonal Antibody

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Catalog Number:MABN84221
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human Dip13 alpha
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200
Molecular Weight:Calculated MW: 80 kDa ; Observed MW: 85 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DIP13 alpha; DP13A; KIAA1428; APPL1; Dip13-alpha; Adapter protein containing PH domain; DCC-interacting protein 13-alpha;;Dip13 alpha

Applications

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200

Immunogen

A synthesized peptide derived from human Dip13 alpha

Target Background

Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell proliferation, immune response, endosomal trafficking and cell metabolism.Regulates signaling pathway leading to cell proliferation through interaction with RAB5A and subunits of the NuRD/MeCP1 complex.

Synonyms:DIP13 alpha; DP13A; KIAA1428; APPL1; Dip13-alpha; Adapter protein containing PH domain; DCC-interacting protein 13-alpha;;Dip13 alpha

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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