Immunological Sciences

Arp3 Rabbit Polyclonal Antibody

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Catalog Number:ABN07160
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human ACTR3. AA range:369-418
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ELISA 1:20000-1:40000
Molecular Weight:47kDa
Purification:Affinity purification
Form:Liquid
Synonyms:ACTR3; ARP3; Actin-related protein 3; Actin-like protein 3

Applications

WB 1:500-1:2000,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human ACTR3. AA range:369-418

Target Background

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013],function:Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament.,similarity:Belongs to the actin family.,similarity:Belongs to the actin family. ARP3 subfamily.,subunit:Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with WHDC1.,

Synonyms:ACTR3; ARP3; Actin-related protein 3; Actin-like protein 3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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