Arrestin-β-1 Rabbit Monoclonal Antibody
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Arrestin-β-1 antibody. The HRP-conjugated Goat anti-Rabbit IgG(H+L) antibody was used to detect the antibody.
| Catalog Number: | MABN87872 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Concentration: | 1mg/ml. The concentration of this product may be batch-dependent. |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | The specific immunogen used to produce this antibody is proprietary information. |
| Reactivity: | Human,Mouse,Rat |
| Applications: | IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000 |
| Molecular Weight: | Calculated MW: 51 kDa; Observed MW: 55 kDa |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Form: | Liquid |
| Synonyms: | ARRB1; ARR1; Beta-arrestin-1; Arrestin beta-1 |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternative spliced transcripts encoding differential isoforms of arrestin beta1 have been described.
Applications
IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000
Immunogen
The specific immunogen used to produce this antibody is proprietary information.
