Arrestin-β-2 Rabbit Monoclonal Antibody
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Arrestin β2 antibody. The HRP-conjugated Goat anti-Rabbit IgG(H+L) antibody was used to detect the antibody.
| Catalog Number: | MABN87873 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Concentration: | 1mg/ml. The concentration of this product may be batch-dependent. |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | The specific immunogen used to produce this antibody is proprietary information. |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:5000; IHC 1:200-1:1000; IF 1:200-1:1000; IP 1:50-1:200; ELISA 1:5000-1:20000 |
| Molecular Weight: | Observed MW: 52kDa |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Form: | Liquid |
| Synonyms: | ARRB2; ARB2; ARR2; Beta-arrestin-2; Arrestin beta-2 |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta2, like arrestin beta1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding differentially isoforms have been found for this gene.[provided by RefSeq, Mar 2012]
Applications
WB 1:1000-1:5000; IHC 1:200-1:1000; IF 1:200-1:1000; IP 1:50-1:200; ELISA 1:5000-1:20000
Immunogen
The specific immunogen used to produce this antibody is proprietary information.
