ASH2L Rabbit Monoclonal Antibody

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Catalog Number:MABN01469
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human ASH2L
Reactivity:Human,Rat
Applications:WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW: 69 kDa; Observed MW: 80 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ASH2; Bre2; ASH2L1; ASH2L2

Applications

WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human ASH2L

Target Background

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

Synonyms:ASH2; Bre2; ASH2L1; ASH2L2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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