Ataxin 1 Rabbit Monoclonal Antibody

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Catalog Number:MABN01686
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Ataxin 1
Reactivity:Mouse
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 87 kDa; Observed MW: 105 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ATX1; SCA1; D6S504E

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

Recombinant protein of human Ataxin 1

Target Background

Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249). In concert with CIC and ATXN1L, involved in brain development .

Synonyms:ATX1; SCA1; D6S504E

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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