Immunological Sciences

ATF2 Mouse Monoclonal Antibody

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Catalog Number:MABN80947
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human ATF2 expressed in E. Coli.
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000
Molecular Weight:55kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HB16; CREB2; TREB7; CRE-BP1; MGC111558; ATF2

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human ATF2 expressed in E. Coli.

Target Background

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.

Synonyms:HB16; CREB2; TREB7; CRE-BP1; MGC111558; ATF2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

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