ATG10 Mouse Monoclonal Antibody

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Catalog Number:MABN82313
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human ATG10 (AA: 1-125) expressed in E. Coli.
Reactivity:Human
Applications:ELISA 1:5000-1:20000
Molecular Weight:25.3kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:APG10; APG10L; pp12616

Applications

ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human ATG10 (AA: 1-125) expressed in E. Coli.

Target Background

Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).

Synonyms:APG10; APG10L; pp12616

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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