Immunological Sciences

ATG4C Mouse Monoclonal Antibody

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Catalog Number:MABN81891
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human ATG4C (AA: 321-458) expressed in E. Coli.
Reactivity:Human
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:52.5kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:APG4C; AUTL1; AUTL3; APG4-C

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human ATG4C (AA: 321-458) expressed in E. Coli.

Target Background

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

Synonyms:APG4C; AUTL1; AUTL3; APG4-C

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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