Immunological Sciences

ATIC Rabbit Monoclonal Antibody

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Catalog Number:MABN86239
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human ATIC
Reactivity:Human, Mouse, Rat
Applications:WB 1:2000-1:20000,IP 1:50-1:100
Molecular Weight:Calculated MW:65 kDa; Observed MW:65 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PURH; AICAR; AICARFT; IMPCHASE; HEL-S-70p

Applications

WB 1:2000-1:20000,IP 1:50-1:100

Immunogen

Recombinant protein of human ATIC

Target Background

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]

Synonyms:PURH; AICAR; AICARFT; IMPCHASE; HEL-S-70p

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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