Immunological Sciences

ATP Citrate Lyase (3D9) Mouse Monoclonal Antibody

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Catalog Number:MABN03438
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG2a
Clone:Monoclonal
Immunogen:A synthetic peptide corresponding to target protein
Reactivity:Human,Mouse,Monkey
Applications:WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100
Molecular Weight:Calculated MW: 121 kDa; Observed MW: 121 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme

Applications

WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100

Immunogen

A synthetic peptide corresponding to target protein

Target Background

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.

Synonyms:ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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