Immunological Sciences

ATP2A1 Mouse Monoclonal Antibody

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Catalog Number:MABN81860
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human ATP2A1 (AA: 487-631) expressed in E. Coli.
Reactivity:Human,Mouse,Monkey
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:110kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ATP2A; SERCA1

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human ATP2A1 (AA: 487-631) expressed in E. Coli.

Target Background

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.

Synonyms:ATP2A; SERCA1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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