AURKA Mouse Monoclonal Antibody

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Catalog Number:MABN80945
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human AURKA expressed in E. Coli.
Reactivity:Human,Rat,Monkey
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000
Molecular Weight:48kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; AURORA2; MGC34538; AURKA

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human AURKA expressed in E. Coli.

Target Background

Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

Synonyms:AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; AURORA2; MGC34538; AURKA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

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