Immunological Sciences

BACE1 Rabbit Monoclonal Antibody

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Catalog Number:MABN01708
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse BACE1
Reactivity:Rat
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 56 kDa; Observed MW: 70 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ASP2; Bace; C76936

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

Recombinant protein of mouse BACE1

Target Background

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type.

Synonyms:ASP2; Bace; C76936

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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