Immunological Sciences

Bak Rabbit Monoclonal Antibody

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Catalog Number:MABN21300
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human Bak
Reactivity:Human,Mouse,Rat,
Applications:WB 1:2000-1:10000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:23kD;Observed MW:23kD
Purification:Protein A
Form:Liquid
Synonyms:BAK1;BAK;BCL2L7;CDN1;Bcl-2 homologous antagonist/killer;Apoptosis reguLator BAK;Bcl-2-like protein 7;Bcl2-L-7

Applications

WB 1:2000-1:10000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide of human Bak

Target Background

Cell localization:Mitochondrion outer membrane.The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008],

Synonyms:BAK1;BAK;BCL2L7;CDN1;Bcl-2 homologous antagonist/killer;Apoptosis reguLator BAK;Bcl-2-like protein 7;Bcl2-L-7

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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