Immunological Sciences

BANP Mouse Monoclonal Antibody

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Catalog Number:MABN86023
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:This BANP antibody is generated from a mouse immunized with a recombinant protein between 30-390 amino acids from human BANP.
Reactivity:Human, Mouse, Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:500
Molecular Weight:56.5kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Protein BANP, BEN domain-containing protein 1, Btg3-associated nuclear protein, Scaffold/matrix-associated region-1-binding protein, BANP, BEND1, SMAR1

Applications

WB 1:500-1:2000,IHC 1:100-1:500

Immunogen

This BANP antibody is generated from a mouse immunized with a recombinant protein between 30-390 amino acids from human BANP.

Target Background

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).

Synonyms:Protein BANP, BEN domain-containing protein 1, Btg3-associated nuclear protein, Scaffold/matrix-associated region-1-binding protein, BANP, BEND1, SMAR1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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