BAX Polyclonal Antibody
Western Blot analysis of Human brain malignant glioma Immunohistochemistry of paraffin-embedded Human tissue, MCF7, Raji and Lovo cell using BAX Polyclonal esophagus cancer using BAX Polyclonal Antibody at dilution Antibody at dilution of 1:300 of 1:30
| Catalog Number: | AB13814 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of human BAX |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:2000; IHC 1:25-1:100 |
| Molecular Weight: | 21 kDa |
| Purification: | Affinity purification |
| Form: | Liquid |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Applications
WB 1:500-1:2000; IHC 1:25-1:100
Immunogen
Recombinant protein of human BAX
