Immunological Sciences

Bcl6 Rabbit Monoclonal Antibody

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Catalog Number:MABN86542
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Bcl6
Reactivity:Human
Applications:WB 1:500-1:2000,IP 1:20-1:50
Molecular Weight:Calculated MW:78 kDa; Observed MW:85 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:BCL5; LAZ3; BCL6A; ZNF51; ZBTB27

Applications

WB 1:500-1:2000,IP 1:20-1:50

Immunogen

A synthetic peptide of human Bcl6

Target Background

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

Synonyms:BCL5; LAZ3; BCL6A; ZNF51; ZBTB27

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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