Beta Arrestin 2 Rabbit Polyclonal Antibody
Western blot analysis of extracts from HeLa cells using Beta Arrestin 2 Rabbit Antibody at 1:1000.
| Catalog Number: | AB-81599 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human Beta Arrestin 2 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:2000,FC 1:200-1:500,IP 1:20-1:50 |
| Molecular Weight: | Observed MW:50 kDa |
| Purification: | Affinity Purification |
| Form: | Liquid |
| Synonyms: | ARB2; ARR2; BARR2 |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Applications
WB 1:500-1:2000,FC 1:200-1:500,IP 1:20-1:50
Immunogen
A synthetic peptide of human Beta Arrestin 2