BMAL1 Rabbit Polyclonal Antibody

Western Blot analysis of K562 cells using BMAL1 Polyclonal Antibody. Secondary
antibody was diluted at 1:20000 cells nucleus extracted

Western Blot analysis of K562 cells using BMAL1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000 cells nucleus extracted

Catalog Number:AB-E4441
Conjugate:unconjated
Size:100 ug
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human BMAL1 around the non-acetylation site of Lys538. AA range:501-550
Reactivity:Human, Mouse, Rat
Applications:Western Blot 1:500- 1:2000 IHC (P): 1:100 - 1:300 Elisa 1:20000
Molecular Weight:69kd
Purification:affinity purified
Form:Liquid
Synonyms:ARNTL; BHLHE5; BMAL1; MOP3; PASD3; Aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein 3; PAS domain-co

Applications

Western Blot 1:500- 1:2000 IHC (P): 1:100 - 1:300 Elisa 1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human BMAL1 around the non-acetylation site of Lys538. AA range:501-550

Target Background

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription  by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns.

Synonyms:ARNTL; BHLHE5; BMAL1; MOP3; PASD3; Aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein 3; PAS domain-co

Storage

Store at -20°C. Avoid repeated freeze-thaw cycles.

Buffer

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Western Blot analysis of K562 cells using BMAL1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000 cells nucleus extracted

Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100

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