BMP4 Mouse Monoclonal Antibody

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Catalog Number:MABN81585
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human BMP4 (AA: 277-408) expressed in E. Coli.
Reactivity:Human,Rat
Applications:WB 1:500-1:2000,ICC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:46.5kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ZYME; BMP2B; OFC11; BMP2B1; MCOPS6

Applications

WB 1:500-1:2000,ICC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human BMP4 (AA: 277-408) expressed in E. Coli.

Target Background

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Synonyms:ZYME; BMP2B; OFC11; BMP2B1; MCOPS6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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