Immunological Sciences

BMP4 Rabbit Monoclonal Antibody

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Catalog Number:MABN85355
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human BMP4
Reactivity:Human
Applications:WB 1:500-1:1000,ICC 1:50-1:200,IP 1:10-1:20
Molecular Weight:Calculated MW: 47 kDa; Observed MW: 47 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:BMP4; BMP2B; DVR4; Bone morphogenetic protein 4; BMP-4; Bone morphogenetic protein 2B; BMP-2B

Applications

WB 1:500-1:1000,ICC 1:50-1:200,IP 1:10-1:20

Immunogen

A synthetic peptide of human BMP4

Target Background

Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation. BMPs belongs to the TGF-β superfamily, playing many diverse functions during development. BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems.

Synonyms:BMP4; BMP2B; DVR4; Bone morphogenetic protein 4; BMP-4; Bone morphogenetic protein 2B; BMP-2B

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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