Immunological Sciences

BRAT1 Rabbit Monoclonal Antibody

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Catalog Number:MABN85358
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human BRAT1
Reactivity:Human
Applications:WB 1:500-1:1000,ICC 1:50-1:200,IP 1:10-1:20
Molecular Weight:Calculated MW: 88 kDa; Observed MW: 88 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1

Applications

WB 1:500-1:1000,ICC 1:50-1:200,IP 1:10-1:20

Immunogen

Recombinant protein of human BRAT1

Target Background

Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371). Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994).

Synonyms:BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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