BRD2 Mouse Monoclonal Antibody

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Catalog Number:MABN81807
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2b
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human BRD2 (AA: 227-364) expressed in E. Coli.
Reactivity:Human,Rat
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:88kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FSH; NAT; RNF3; FSRG1; RING3; D6S113E; O27.1.1

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human BRD2 (AA: 227-364) expressed in E. Coli.

Target Background

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.

Synonyms:FSH; NAT; RNF3; FSRG1; RING3; D6S113E; O27.1.1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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