Immunological Sciences

BRD2 Rabbit Monoclonal Antibody

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Catalog Number:MABN87428
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human BRD2
Reactivity:Human
Applications:WB 1:1000-1:2000,IHC 1:50-1:100,ICC/IF 1:20-1:50,FC 1:50-1:100
Molecular Weight:Calculated MW:88 kDa; Observed MW:110 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FSH; NAT; RNF3; FSRG1; RING3; D6S113E; O27.1.1; BRD2-IT1

Applications

WB 1:1000-1:2000,IHC 1:50-1:100,ICC/IF 1:20-1:50,FC 1:50-1:100

Immunogen

A synthetic peptide of human BRD2

Target Background

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]

Synonyms:FSH; NAT; RNF3; FSRG1; RING3; D6S113E; O27.1.1; BRD2-IT1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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